FCER1A
FCER1A | |||||||||||||||||
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المعرفات | |||||||||||||||||
الأسماء المستعارة | FCER1A, FCE1A, FcERI, Fc fragment of IgE receptor Ia | ||||||||||||||||
معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 147140 MGI: MGI:95494 HomoloGene: 1516 GeneCards: 2205 | ||||||||||||||||
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نمط التعبير عن الحمض النووي الريبوزي | |||||||||||||||||
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المزيد من بيانات التعبير المرجعية | |||||||||||||||||
أورثولوج | |||||||||||||||||
الأنواع | الإنسان | الفأر | |||||||||||||||
أنتريه | 2205 | 14125 | |||||||||||||||
Ensembl | ENSG00000179639 | ENSMUSG00000005339 | |||||||||||||||
يونيبروت | |||||||||||||||||
RefSeq (مرسال ر.ن.ا.) | |||||||||||||||||
RefSeq (بروتين) | |||||||||||||||||
الموقع (UCSC | n/a | Chr 1: 173.05 – 173.05 Mb | |||||||||||||||
بحث ببمد | [1] | [2] | |||||||||||||||
ويكي بيانات | |||||||||||||||||
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FCER1A (Fc fragment of IgE receptor Ia) هوَ بروتين يُشَفر بواسطة جين FCER1A في الإنسان.[1]
الوظيفة[عدل]
![]() | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية[عدل]
![]() | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع[عدل]
- ^ "Characterization of the gene for the human high affinity IgE receptor (Fc epsilon RI) alpha-chain". J. Immunol. 151 (11): 6166–74. ديسمبر 1993. PMID 8245459. مؤرشف من الأصل في 2008-10-06.
قراءة متعمقة[عدل]
- Gounni AS (2006). "The high-affinity IgE receptor (FcepsilonRI): a critical regulator of airway smooth muscle cells?". Am. J. Physiol. Lung Cell Mol. Physiol. 291 (3): L312–21. doi:10.1152/ajplung.00005.2006. PMID 16581830.
- "A modeling study of the alpha-subunit of human high-affinity receptor for immunoglobulin-E". Receptor. 2 (2): 129–44. 1993. PMID 1472946.
- "Epidermal Langerhans cells from normal human skin bind monomeric IgE via Fc epsilon RI". J. Exp. Med. 175 (5): 1353–65. 1992. doi:10.1084/jem.175.5.1353. PMC 2119204. PMID 1533243.
- "The gene and cDNA for the human high affinity immunoglobulin E receptor beta chain and expression of the complete human receptor". J. Biol. Chem. 267 (18): 12782–7. 1992. PMID 1535625.
- "The human genes for the alpha and gamma subunits of the mast cell receptor for immunoglobulin E are located on human chromosome band 1q23". Immunogenetics. 32 (3): 183–6. 1990. doi:10.1007/BF02114971. PMID 2146219.
- "Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products". Proc. Natl. Acad. Sci. U.S.A. 85 (6): 1907–11. 1988. doi:10.1073/pnas.85.6.1907. PMC 279890. PMID 2964640.
- "Isolation of the gene coding for the alpha subunit of the human high affinity IgE receptor". Nucleic Acids Res. 16 (8): 3584. 1988. doi:10.1093/nar/16.8.3584. PMC 336524. PMID 2967464.
- "High-level expression of the truncated alpha chain of human high-affinity receptor for IgE as a soluble form by baculovirus-infected insect cells. Biochemical characterization of the recombinant product". Eur. J. Biochem. 220 (2): 593–8. 1994. doi:10.1111/j.1432-1033.1994.tb18660.x. PMID 8125119.
- "Characterization of the gene for the human high affinity IgE receptor (Fc epsilon RI) alpha-chain". J. Immunol. 151 (11): 6166–74. 1994. PMID 8245459.
- "Fine mapping of the human pentraxin gene region on chromosome 1q23". Immunogenetics. 44 (1): 62–9. 1996. doi:10.1007/BF02602657. PMID 8613143.
- "Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation". J. Immunol. 157 (2): 607–16. 1996. PMID 8752908.
- "Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc epsilonRI alpha". Nature. 406 (6793): 259–66. 2000. doi:10.1038/35018500. PMID 10917520.
- "Cloning of full-length genomic DNA encoding human FcepsilonRI alpha-chain and its transcriptional regulation". Biochem. Biophys. Res. Commun. 284 (4): 1056–64. 2001. doi:10.1006/bbrc.2001.5079. PMID 11409901.
- "The analysis of the human high affinity IgE receptor Fc epsilon Ri alpha from multiple crystal forms". J. Mol. Biol. 311 (5): 1049–62. 2001. doi:10.1006/jmbi.2001.4929. PMID 11531339.
- "Sequence variants in the FcepsilonRI alpha chain gene". J. Appl. Physiol. 93 (1): 37–41. 2002. doi:10.1152/japplphysiol.00993.2001. PMID 12070183.
- "Regulation of FcepsilonRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells". Blood. 100 (6): 2138–44. 2002. doi:10.1182/blood-2001-12-0340. PMID 12200378.
- "Transcriptional regulation of the human high affinity IgE receptor alpha-chain gene". Mol. Immunol. 38 (16–18): 1193–9. 2003. doi:10.1016/S0161-5890(02)00062-7. PMID 12217383.
- "Efficient folding of the FcepsilonRI alpha-chain membrane-proximal domain D2 depends on the presence of the N-terminal domain D1". J. Mol. Biol. 322 (4): 815–25. 2002. doi:10.1016/S0022-2836(02)00853-7. PMID 12270716.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- "Regulation of the human Fc epsilon RI alpha-chain distal promoter". J. Immunol. 170 (7): 3732–8. 2003. doi:10.4049/jimmunol.170.7.3732. PMID 12646639.