Phosducin
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
Phosducin (Phosducin) هوَ بروتين يُشَفر بواسطة جين Phosducin في الإنسان.[1]
الوظيفة[عدل]

الأهمية السريرية[عدل]

المراجع[عدل]
- ^ "Entrez Gene: PDC phosducin". مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة[عدل]
- Abe T، Nakabayashi H، Tamada H، وآخرون. (1990). "Analysis of the human, bovine and rat 33-kDa proteins and cDNA in retina and pineal gland". Gene. 91 (2): 209–15. PMID 2210381. doi:10.1016/0378-1119(90)90090-E.
- Watanabe Y، Kawasaki K، Miki N، Kuo CH (1990). "Isolation and analysis of the human MEKA gene encoding a retina-specific protein". Biochem. Biophys. Res. Commun. 170 (2): 951–6. PMID 2383274. doi:10.1016/0006-291X(90)92183-Z.
- Lee RH، Brown BM، Lolley RN (1990). "Protein kinase A phosphorylates retinal phosducin on serine 73 in situ". J. Biol. Chem. 265 (26): 15860–6. PMID 2394752.
- Hawes BE، Touhara K، Kurose H، وآخرون. (1994). "Determination of the G beta gamma-binding domain of phosducin. A regulatable modulator of G beta gamma signaling". J. Biol. Chem. 269 (47): 29825–30. PMID 7961975.
- Abe T، Kikuchi T، Shinohara T (1994). "The sequence of the human phosducin gene (PDC) and its 5'-flanking region". Genomics. 19 (2): 369–72. PMID 8188267. doi:10.1006/geno.1994.1072.
- Sparkes RS، Lee RH، Shinohara T، وآخرون. (1994). "Assignment of the phosducin (PDC) gene to human chromosome 1q25-1q32.1 by somatic cell hybridization and in situ hybridization". Genomics. 18 (2): 426–8. PMID 8288249. doi:10.1006/geno.1993.1490.
- Ding C، Li X، Griffin CA، وآخرون. (1994). "The gene for human phosducin (PDC), a soluble protein that binds G-protein beta gamma dimers, maps to 1q25-q31.1". Genomics. 18 (2): 457–9. PMID 8288259. doi:10.1006/geno.1993.1501.
- Boekhoff I، Touhara K، Danner S، وآخرون. (1997). "Phosducin, potential role in modulation of olfactory signaling". J. Biol. Chem. 272 (7): 4606–12. PMID 9020189. doi:10.1074/jbc.272.7.4606.
- Barhite S، Thibault C، Miles MF (1998). "Phosducin-like protein (PhLP), a regulator of G beta gamma function, interacts with the proteasomal protein SUG1". Biochim. Biophys. Acta. 1402 (1): 95–101. PMID 9551090. doi:10.1016/S0167-4889(97)00141-9.
- Zhu X، Craft CM (1998). "Interaction of phosducin and phosducin isoforms with a 26S proteasomal subunit, SUG1". Mol. Vis. 4: 13. PMID 9701609.
- Craft CM، Xu J، Slepak VZ، وآخرون. (1998). "PhLPs and PhLOPs in the phosducin family of G beta gamma binding proteins". Biochemistry. 37 (45): 15758–72. PMID 9843381. doi:10.1021/bi980921a.
- Carpten JD، Makalowska I، Robbins CM، وآخرون. (2000). "A 6-Mb high-resolution physical and transcription map encompassing the hereditary prostate cancer 1 (HPC1) region". Genomics. 64 (1): 1–14. PMID 10708513. doi:10.1006/geno.1999.6051.
- Zhu X، Craft CM (2000). "The carboxyl terminal domain of phosducin functions as a transcriptional activator". Biochem. Biophys. Res. Commun. 270 (2): 504–9. PMID 10753654. doi:10.1006/bbrc.2000.2414.
- Zhu X، Craft CM (2000). "Modulation of CRX transactivation activity by phosducin isoforms". Mol. Cell. Biol. 20 (14): 5216–26. PMC 85970
. PMID 10866677. doi:10.1128/MCB.20.14.5216-5226.2000.
- Ruiz-Gómez A، Humrich J، Murga C، وآخرون. (2000). "Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2". J. Biol. Chem. 275 (38): 29724–30. PMID 10884381. doi:10.1074/jbc.M001864200.
- Nakano K، Chen J، Tarr GE، وآخرون. (2001). "Rethinking the role of phosducin: light-regulated binding of phosducin to 14-3-3 in rod inner segments". Proc. Natl. Acad. Sci. U.S.A. 98 (8): 4693–8. PMC 31896
. PMID 11287646. doi:10.1073/pnas.071067198.
- Thulin CD، Savage JR، McLaughlin JN، وآخرون. (2001). "Modulation of the G protein regulator phosducin by Ca2+/calmodulin-dependent protein kinase II phosphorylation and 14-3-3 protein binding". J. Biol. Chem. 276 (26): 23805–15. PMID 11331285. doi:10.1074/jbc.M101482200.
- Wistow G، Bernstein SL، Wyatt MK، وآخرون. (2002). "Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts". Mol. Vis. 8: 196–204. PMID 12107411.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899.
- Margulis A، Dang L، Pulukuri S، وآخرون. (2002). "Presence of phosducin in the nuclei of bovine retinal cells". Mol. Vis. 8: 477–82. PMID 12500174.
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