S100P
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
S100P (S100 calcium binding protein P) هوَ بروتين يُشَفر بواسطة جين S100P في الإنسان.[1][2][3]
الوظيفة[عدل]
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.الأهمية السريرية[عدل]
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.المراجع[عدل]
- ^ Engelkamp D، Schäfer BW، Mattei MG، Erne P، Heizmann CW (Aug 1993). "Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E". Proc Natl Acad Sci U S A. 90 (14): 6547–51. PMC 46969
. PMID 8341667. doi:10.1073/pnas.90.14.6547.
- ^ "Entrez Gene: S100P S100 calcium binding protein P".
- ^ Schäfer BW، Wicki R، Engelkamp D، Mattei MG، Heizmann CW (Jun 1995). "Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family". Genomics. 25 (3): 638–43. PMID 7759097. doi:10.1016/0888-7543(95)80005-7.
قراءة متعمقة[عدل]
- Schäfer BW، Heizmann CW (1996). "The S100 family of EF-hand calcium-binding proteins: functions and pathology.". Trends Biochem. Sci. 21 (4): 134–40. PMID 8701470. doi:10.1016/S0968-0004(96)80167-8.
- Emoto Y، Kobayashi R، Akatsuka H، Hidaka H (1992). "Purification and characterization of a new member of the S-100 protein family from human placenta.". Biochem. Biophys. Res. Commun. 182 (3): 1246–53. PMID 1540168. doi:10.1016/0006-291X(92)91865-N.
- Becker T، Gerke V، Kube E، Weber K (1992). "S100P, a novel Ca(2+)-binding protein from human placenta. cDNA cloning, recombinant protein expression and Ca2+ binding properties.". Eur. J. Biochem. 207 (2): 541–7. PMID 1633809. doi:10.1111/j.1432-1033.1992.tb17080.x.
- Gribenko AV، Makhatadze GI (1998). "Oligomerization and divalent ion binding properties of the S100P protein: a Ca2+/Mg2+-switch model.". J. Mol. Biol. 283 (3): 679–94. PMID 9784376. doi:10.1006/jmbi.1998.2116.
- Koltzscher M، Gerke V (2000). "Identification of hydrophobic amino acid residues involved in the formation of S100P homodimers in vivo.". Biochemistry. 39 (31): 9533–9. PMID 10924150. doi:10.1021/bi000257.
- Harvell JD، Fulton R، Jones CD، Terris DJ، Warnke RA (2001). "Composite dendritic cell neoplasm (NOS) and small lymphocytic lymphoma.". Appl. Immunohistochem. Mol. Morphol. 8 (4): 322–8. PMID 11127925. doi:10.1097/00022744-200012000-00010.
- Gribenko AV، Hopper JE، Makhatadze GI (2002). "Molecular characterization and tissue distribution of a novel member of the S100 family of EF-hand proteins.". Biochemistry. 40 (51): 15538–48. PMID 11747429. doi:10.1021/bi0114731.
- Gribenko AV، Guzmán-Casado M، Lopez MM، Makhatadze GI (2003). "Conformational and thermodynamic properties of peptide binding to the human S100P protein.". Protein Sci. 11 (6): 1367–75. PMC 2373636. PMID 12021435. doi:10.1110/ps.0202202.
- Filipek A، Jastrzebska B، Nowotny M، Kuznicki J (2002). "CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family.". J. Biol. Chem. 277 (32): 28848–52. PMID 12042313. doi:10.1074/jbc.M203602200.
- Zhang H، Wang G، Ding Y، Wang Z، Barraclough R، Rudland PS، Fernig DG، Rao Z (2003). "The crystal structure at 2A resolution of the Ca2+ -binding protein S100P.". J. Mol. Biol. 325 (4): 785–94. PMID 12507480. doi:10.1016/S0022-2836(02)01278-0.
- Nowotny M، Spiechowicz M، Jastrzebska B، Filipek A، Kitagawa K، Kuznicki J (2003). "Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins.". J. Biol. Chem. 278 (29): 26923–8. PMID 12746458. doi:10.1074/jbc.M211518200.
- Koltzscher M، Neumann C، König S، Gerke V (2004). "Ca2+-dependent binding and activation of dormant ezrin by dimeric S100P.". Mol. Biol. Cell. 14 (6): 2372–84. PMC 194886. PMID 12808036. doi:10.1091/mbc.E02-09-0553.
- Arumugam T، Simeone DM، Schmidt AM، Logsdon CD (2004). "S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE).". J. Biol. Chem. 279 (7): 5059–65. PMID 14617629. doi:10.1074/jbc.M310124200.
- Jin G، Wang S، Hu X، Jing Z، Chen J، Ying K، Xie Y، Mao Y (2004). "Characterization of the tissue-specific expression of the s100P gene which encodes an EF-hand Ca2+-binding protein.". Mol. Biol. Rep. 30 (4): 243–8. PMID 14672411. doi:10.1023/A:1026311423326.
- Sato N، Fukushima N، Matsubayashi H، Goggins M (2004). "Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling.". Oncogene. 23 (8): 1531–8. PMID 14716296. doi:10.1038/sj.onc.1207269.
- Lee YC، Volk DE، Thiviyanathan V، Kleerekoper Q، Gribenko AV، Zhang S، Gorenstein DG، Makhatadze GI، Luxon BA (2005). "NMR structure of the Apo-S100P protein.". J. Biomol. NMR. 29 (3): 399–402. PMID 15213440. doi:10.1023/B:JNMR.0000032617.88899.4b.
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