TRAP1
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
TRAP1 (TNF receptor associated protein 1) هوَ بروتين يُشَفر بواسطة جين TRAP1 في الإنسان.[1][2][3]
الوظيفة[عدل]

الأهمية السريرية[عدل]

المراجع[عدل]
- ^ "Entrez Gene: TRAP1 TNF receptor-associated protein 1".
- ^ Felts SJ، Owen BA، Nguyen P، Trepel J، Donner DB، Toft DO (March 2000). "The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties". J Biol Chem. 275 (5): 3305–12. PMID 10652318. doi:10.1074/jbc.275.5.3305.
- ^ Song HY، Dunbar JD، Zhang YX، Guo D، Donner DB (March 1995). "Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor". J Biol Chem. 270 (8): 3574–81. PMID 7876093. doi:10.1074/jbc.270.8.3574.
قراءة متعمقة[عدل]
- Maruyama K، Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298. doi:10.1016/0378-1119(94)90802-8.
- Chen CF، Chen Y، Dai K، وآخرون. (1996). "A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock". Mol. Cell. Biol. 16 (9): 4691–9. PMC 231469
. PMID 8756626.
- Suzuki Y، Yoshitomo-Nakagawa K، Maruyama K، وآخرون. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3.
- Charng MJ، Zhang D، Kinnunen P، Schneider MD (1998). "A novel protein distinguishes between quiescent and activated forms of the type I transforming growth factor beta receptor". J. Biol. Chem. 273 (16): 9365–8. PMID 9545258. doi:10.1074/jbc.273.16.9365.
- Simmons AD، Musy MM، Lopes CS، وآخرون. (1999). "A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses". Hum. Mol. Genet. 8 (12): 2155–64. PMID 10545594. doi:10.1093/hmg/8.12.2155.
- Wurthner JU، Frank DB، Felici A، وآخرون. (2001). "Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone". J. Biol. Chem. 276 (22): 19495–502. PMID 11278302. doi:10.1074/jbc.M006473200.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899.
- Ota T، Suzuki Y، Nishikawa T، وآخرون. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285.
- Masuda Y، Shima G، Aiuchi T، وآخرون. (2004). "Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin". J. Biol. Chem. 279 (41): 42503–15. PMID 15292218. doi:10.1074/jbc.M404256200.
- Gerhard DS، Wagner L، Feingold EA، وآخرون. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928
. PMID 15489334. doi:10.1101/gr.2596504.
- Brown V، Brown RA، Ozinsky A، وآخرون. (2006). "Binding specificity of Toll-like receptor cytoplasmic domains". Eur. J. Immunol. 36 (3): 742–53. PMC 2762736
. PMID 16482509. doi:10.1002/eji.200535158.
- Im CN، Lee JS، Zheng Y، Seo JS (2007). "Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species". J. Cell. Biochem. 100 (2): 474–86. PMID 16927372. doi:10.1002/jcb.21064.
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