RAB2A
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
RAB2A (RAB2A, member RAS oncogene family) هوَ بروتين يُشَفر بواسطة جين RAB2A في الإنسان.[1]
الوظيفة[عدل]

الأهمية السريرية[عدل]

المراجع[عدل]
- ^ "Entrez Gene: RAB2A RAB2A, member RAS oncogene family". مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة[عدل]
- Khosravi-Far R، Lutz RJ، Cox AD، Conroy L، Bourne JR، Sinensky M، Balch WE، Buss JE، Der CJ (Jul 1991). "Isoprenoid modification of rab proteins terminating in CC or CXC motifs". Proceedings of the National Academy of Sciences of the United States of America. 88 (14): 6264–8. PMC 52063
. PMID 1648736. doi:10.1073/pnas.88.14.6264.
- Zahraoui A، Touchot N، Chardin P، Tavitian A (Jul 1989). "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion". The Journal of Biological Chemistry. 264 (21): 12394–401. PMID 2501306.
- Tachibana K، Umezawa A، Kato S، Takano T (Nov 1988). "Nucleotide sequence of a new YPT1-related human cDNA which belongs to the ras gene superfamily". Nucleic Acids Research. 16 (21): 10368. PMC 338870
. PMID 3057444. doi:10.1093/nar/16.21.10368.
- Andersson B، Wentland MA، Ricafrente JY، Liu W، Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. PMID 8619474. doi:10.1006/abio.1996.0138.
- Tisdale EJ، Balch WE (Nov 1996). "Rab2 is essential for the maturation of pre-Golgi intermediates". The Journal of Biological Chemistry. 271 (46): 29372–9. PMID 8910601. doi:10.1074/jbc.271.46.29372.
- Yu W، Andersson B، Worley KC، Muzny DM، Ding Y، Liu W، Ricafrente JY، Wentland MA، Lennon G، Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. PMC 139146
. PMID 9110174. doi:10.1101/gr.7.4.353.
- de Leeuw HP، Koster PM، Calafat J، Janssen H، van Zonneveld AJ، van Mourik JA، Voorberg J (Oct 1998). "Small GTP-binding proteins in human endothelial cells". British Journal of Haematology. 103 (1): 15–9. PMID 9792283. doi:10.1046/j.1365-2141.1998.00965.x.
- Shisheva A، Chinni SR، DeMarco C (Sep 1999). "General role of GDP dissociation inhibitor 2 in membrane release of Rab proteins: modulations of its functional interactions by in vitro and in vivo structural modifications". Biochemistry. 38 (36): 11711–21. PMID 10512627. doi:10.1021/bi990200r.
- Caillol N، Pasqualini E، Lloubes R، Lombardo D (Sep 2000). "Impairment of bile salt-dependent lipase secretion in human pancreatic tumoral SOJ-6 cells". Journal of Cellular Biochemistry. 79 (4): 628–47. PMID 10996854. doi:10.1002/1097-4644(20001215)79:4<628::AID-JCB120>3.0.CO;2-T.
- Short B، Preisinger C، Körner R، Kopajtich R، Byron O، Barr FA (Dec 2001). "A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic". The Journal of Cell Biology. 155 (6): 877–83. PMC 2150909
. PMID 11739401. doi:10.1083/jcb.200108079.
- Ni X، Ma Y، Cheng H، Jiang M، Guo L، Ji C، Gu S، Cao Y، Xie Y، Mao Y (2002). "Molecular cloning and characterization of a novel human Rab ( Rab2B) gene". Journal of Human Genetics. 47 (10): 548–51. PMID 12376746. doi:10.1007/s100380200083.
- Tisdale EJ (Dec 2003). "Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation". The Journal of Biological Chemistry. 278 (52): 52524–30. PMID 14570876. doi:10.1074/jbc.M309343200.
- Tisdale EJ، Kelly C، Artalejo CR (Dec 2004). "Glyceraldehyde-3-phosphate dehydrogenase interacts with Rab2 and plays an essential role in endoplasmic reticulum to Golgi transport exclusive of its glycolytic activity". The Journal of Biological Chemistry. 279 (52): 54046–52. PMID 15485821. doi:10.1074/jbc.M409472200.
- Chi A، Valencia JC، Hu ZZ، Watabe H، Yamaguchi H، Mangini NJ، Huang H، Canfield VA، Cheng KC، Yang F، Abe R، Yamagishi S، Shabanowitz J، Hearing VJ، Wu C، Appella E، Hunt DF (Nov 2006). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes". Journal of Proteome Research. 5 (11): 3135–44. PMID 17081065. doi:10.1021/pr060363j.
- Dong C، Wu G (Nov 2007). "Regulation of anterograde transport of adrenergic and angiotensin II receptors by Rab2 and Rab6 GTPases". Cellular Signalling. 19 (11): 2388–99. PMC 2072516
. PMID 17716866. doi:10.1016/j.cellsig.2007.07.017.
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