CRTC2
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
CRTC2 (CREB regulated transcription coactivator 2) هوَ بروتين يُشَفر بواسطة جين CRTC2 في الإنسان.[1][2][3]
الوظيفة[عدل]

الأهمية السريرية[عدل]

المراجع[عدل]
- ^ "TORCs: transducers of regulated CREB activity". Molecular Cell. 12 (2): 413–23. Aug 2003. doi:10.1016/j.molcel.2003.08.013. PMID 14536081. الوسيط
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تم تجاهله (مساعدة) - ^ "Entrez Gene: CRTC2 CREB regulated transcription coactivator 2". مؤرشف من الأصل في 05 ديسمبر 2010. الوسيط
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تم تجاهله (مساعدة) - ^ "Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells". Proceedings of the National Academy of Sciences of the United States of America. 100 (21): 12147–52. Oct 2003. doi:10.1073/pnas.1932773100. PMC 218727. PMID 14506290. الوسيط
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تم تجاهله (مساعدة)
قراءة متعمقة[عدل]
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. Jan 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. الوسيط
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تم تجاهله (مساعدة) - "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. Oct 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. الوسيط
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تم تجاهله (مساعدة) - "Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells". Proceedings of the National Academy of Sciences of the United States of America. 100 (21): 12147–52. Oct 2003. doi:10.1073/pnas.1932773100. PMC 218727. PMID 14506290. الوسيط
|CitationClass=
تم تجاهله (مساعدة) - "TORCs: transducers of regulated CREB activity". Molecular Cell. 12 (2): 413–23. Aug 2003. doi:10.1016/j.molcel.2003.08.013. PMID 14536081. الوسيط
|CitationClass=
تم تجاهله (مساعدة) - "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Current Biology. 14 (16): 1436–50. Aug 2004. doi:10.1016/j.cub.2004.07.051. PMID 15324660. الوسيط
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تم تجاهله (مساعدة) - "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector". Cell. 119 (1): 61–74. Oct 2004. doi:10.1016/j.cell.2004.09.015. PMID 15454081. الوسيط
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تم تجاهله (مساعدة) - "14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK". Journal of Cell Science. 118 (Pt 23): 5661–73. Dec 2005. doi:10.1242/jcs.02670. PMID 16306228. الوسيط
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تم تجاهله (مساعدة) - "TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeats". Journal of Virology. 80 (14): 7052–9. Jul 2006. doi:10.1128/JVI.00103-06. PMC 1489057. PMID 16809310. الوسيط
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تم تجاهله (مساعدة) - "Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells". Proceedings of the National Academy of Sciences of the United States of America. 103 (39): 14379–84. Sep 2006. doi:10.1073/pnas.0606714103. PMC 1569674. PMID 16980408. الوسيط
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تم تجاهله (مساعدة) - "Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity". Genes & Development. 20 (20): 2820–32. Oct 2006. doi:10.1101/gad.1461206. PMC 1619946. PMID 17043309. الوسيط
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تم تجاهله (مساعدة) - "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. 2007. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. الوسيط
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تم تجاهله (مساعدة) - "Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression". The EMBO Journal. 26 (12): 2880–9. Jun 2007. doi:10.1038/sj.emboj.7601715. PMC 1894761. PMID 17476304. الوسيط
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تم تجاهله (مساعدة) - "TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation". Proceedings of the National Academy of Sciences of the United States of America. 104 (24): 10175–80. Jun 2007. doi:10.1073/pnas.0704170104. PMC 1891214. PMID 17548807. الوسيط
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