PLEKHO1
PLEKHO1 (Pleckstrin homology domain containing O1) هوَ بروتين يُشَفر بواسطة جين PLEKHO1 في الإنسان.[1][2]
الوظيفة[عدل]
![]() | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية[عدل]
![]() | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع[عدل]
- ^ "Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2". J Biol Chem. 275 (19): 14295–306. يونيو 2000. doi:10.1074/jbc.275.19.14295. PMID 10799509.
- ^ "Entrez Gene: PLEKHO1 pleckstrin homology domain containing, family O member 1". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة[عدل]
- "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. 2001. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The Pleckstrin homology domain of CK2 interacting protein-1 is required for interactions and recruitment of protein kinase CK2 to the plasma membrane". J. Biol. Chem. 279 (40): 42114–27. 2004. doi:10.1074/jbc.M407628200. PMID 15254037.
- "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. 2004. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- "Role for the pleckstrin homology domain-containing protein CKIP-1 in AP-1 regulation and apoptosis". EMBO J. 24 (4): 766–78. 2005. doi:10.1038/sj.emboj.7600532. PMC 549613. PMID 15706351.
- "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. 2005. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153.
- "The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein". Mol. Cell. Biol. 25 (9): 3519–34. 2005. doi:10.1128/MCB.25.9.3519-3534.2005. PMC 1084316. PMID 15831458.
- "CKIP-1 recruits nuclear ATM partially to the plasma membrane through interaction with ATM". Cell. Signal. 18 (9): 1386–95. 2007. doi:10.1016/j.cellsig.2005.10.017. PMID 16325375.
- "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. 2006. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. 2006. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
- "The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein". J. Biol. Chem. 281 (47): 36347–59. 2007. doi:10.1074/jbc.M607595200. PMC 2583070. PMID 16987810.
- "The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling". Cell. Signal. 19 (5): 932–44. 2007. doi:10.1016/j.cellsig.2006.11.002. PMID 17197158.
- "Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo". Cancer Res. 67 (20): 9666–76. 2007. doi:10.1158/0008-5472.CAN-07-1050. PMID 17942896.