RFX5
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
RFX5 (Regulatory factor X5) هوَ بروتين يُشَفر بواسطة جين RFX5 في الإنسان.[1]
الوظيفة[عدل]

الأهمية السريرية[عدل]

المراجع[عدل]
- ^ "Entrez Gene: RFX5 regulatory factor X, 5 (influences HLA class II expression)". مؤرشف من الأصل في 05 ديسمبر 2010. الوسيط
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تم تجاهله (مساعدة)
قراءة متعمقة[عدل]
- "The bare lymphocyte syndrome and the regulation of MHC expression". Annual Review of Immunology. 19: 331–73. 2001. doi:10.1146/annurev.immunol.19.1.331. PMID 11244040. الوسيط
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تم تجاهله (مساعدة) - "A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)". Genes & Development. 9 (9): 1021–32. May 1995. doi:10.1101/gad.9.9.1021. PMID 7744245. الوسيط
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تم تجاهله (مساعدة) - "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. Jan 1994. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. الوسيط
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تم تجاهله (مساعدة) - "RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency". The EMBO Journal. 16 (5): 1045–55. Mar 1997. doi:10.1093/emboj/16.5.1045. PMC 1169704. PMID 9118943. الوسيط
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تم تجاهله (مساعدة) - "Specific complex formation between the type II bare lymphocyte syndrome-associated transactivators CIITA and RFX5". Proceedings of the National Academy of Sciences of the United States of America. 94 (12): 6330–4. Jun 1997. doi:10.1073/pnas.94.12.6330. PMC 21049. PMID 9177217. الوسيط
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تم تجاهله (مساعدة) - "Regulatory factor X, a bare lymphocyte syndrome transcription factor, is a multimeric phosphoprotein complex". Journal of Immunology. 158 (12): 5841–8. Jun 1997. PMID 9190936. الوسيط
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تم تجاهله (مساعدة) - "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. Oct 1997. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. الوسيط
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تم تجاهله (مساعدة) - "A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients". Nature Genetics. 20 (3): 273–7. Nov 1998. doi:10.1038/3081. PMID 9806546. الوسيط
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تم تجاهله (مساعدة) - "RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency". Immunity. 10 (2): 153–62. Feb 1999. doi:10.1016/S1074-7613(00)80016-3. PMID 10072068. الوسيط
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تم تجاهله (مساعدة) - "Molecular analysis of an MHC class II deficiency patient reveals a novel mutation in the RFX5 gene". Immunogenetics. 49 (4): 338–45. Apr 1999. doi:10.1007/s002510050501. PMID 10079298. الوسيط
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تم تجاهله (مساعدة) - "A functionally essential domain of RFX5 mediates activation of major histocompatibility complex class II promoters by promoting cooperative binding between RFX and NF-Y". Molecular and Cellular Biology. 20 (10): 3364–76. May 2000. doi:10.1128/MCB.20.10.3364-3376.2000. PMC 85629. PMID 10779326. الوسيط
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تم تجاهله (مساعدة) - "Mutations in the bare lymphocyte syndrome define critical steps in the assembly of the regulatory factor X complex". Molecular and Cellular Biology. 20 (12): 4455–61. Jun 2000. doi:10.1128/MCB.20.12.4455-4461.2000. PMC 85813. PMID 10825209. الوسيط
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تم تجاهله (مساعدة) - "The RFX family interacts at the collagen (COL1A2) start site and represses transcription". The Journal of Biological Chemistry. 277 (28): 24926–37. Jul 2002. doi:10.1074/jbc.M111712200. PMID 11986307. الوسيط
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تم تجاهله (مساعدة) - "Mutation in a winged-helix DNA-binding motif causes atypical bare lymphocyte syndrome". Nature Immunology. 3 (11): 1075–81. Nov 2002. doi:10.1038/ni840. PMID 12368908. الوسيط
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تم تجاهله (مساعدة) - "Interferon gamma repression of collagen (COL1A2) transcription is mediated by the RFX5 complex". The Journal of Biological Chemistry. 278 (49): 49134–44. Dec 2003. doi:10.1074/jbc.M309003200. PMID 12968017. الوسيط
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تم تجاهله (مساعدة) - "A hierarchy of nuclear localization signals governs the import of the regulatory factor X complex subunits and MHC class II expression". Journal of Immunology. 173 (1): 410–9. Jul 2004. doi:10.4049/jimmunol.173.1.410. PMID 15210800. الوسيط
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تم تجاهله (مساعدة) - "Identification of phosphorylation sites in protein kinase A substrates using artificial neural networks and mass spectrometry". Journal of Proteome Research. 3 (3): 426–33. 2004. doi:10.1021/pr0341033. PMID 15253423. الوسيط
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