PRDM2
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هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
هذا القسم فارغ أو غير مكتمل، ساهم بتحريره.
PRDM2 (PR/SET domain 2) هوَ بروتين يُشَفر بواسطة جين PRDM2 في الإنسان.[1][2]
الوظيفة[عدل]

الأهمية السريرية[عدل]

المراجع[عدل]
- ^ "The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein". Proceedings of the National Academy of Sciences of the United States of America. 92 (10): 4467–71. May 1995. doi:10.1073/pnas.92.10.4467. PMC 41965. PMID 7538672. الوسيط
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تم تجاهله (مساعدة) - ^ "Entrez Gene: PRDM2 PR domain containing 2, with ZNF domain". مؤرشف من الأصل في 05 ديسمبر 2010. الوسيط
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تم تجاهله (مساعدة)
قراءة متعمقة[عدل]
- "Identification and cloning of the G3B cDNA encoding a 3' segment of a protein binding to GATA-3". Gene. 163 (2): 329–30. Oct 1995. doi:10.1016/0378-1119(95)00420-B. PMID 7590293. الوسيط
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تم تجاهله (مساعدة) - "cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene". European Journal of Biochemistry / FEBS. 235 (3): 471–9. Feb 1996. doi:10.1111/j.1432-1033.1996.00471.x. PMID 8654390. الوسيط
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تم تجاهله (مساعدة) - "Physical mapping of the retinoblastoma interacting zinc finger gene RIZ to D1S228 on chromosome 1p36". Genomics. 34 (1): 119–21. May 1996. doi:10.1006/geno.1996.0249. PMID 8661032. الوسيط
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تم تجاهله (مساعدة) - "The retinoblastoma interacting zinc finger gene RIZ produces a PR domain-lacking product through an internal promoter". The Journal of Biological Chemistry. 272 (5): 2984–91. Jan 1997. doi:10.1074/jbc.272.5.2984. PMID 9006946. الوسيط
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تم تجاهله (مساعدة) - "Transcriptional repression mediated by the PR domain zinc finger gene RIZ". The Journal of Biological Chemistry. 272 (42): 26360–6. Oct 1997. doi:10.1074/jbc.272.42.26360. PMID 9334209. الوسيط
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تم تجاهله (مساعدة) - "RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis". Cancer Research. 58 (19): 4238–44. Oct 1998. PMID 9766644. الوسيط
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تم تجاهله (مساعدة) - "The retinoblastoma-interacting zinc-finger protein RIZ is a downstream effector of estrogen action". Proceedings of the National Academy of Sciences of the United States of America. 97 (7): 3130–5. Mar 2000. doi:10.1073/pnas.050015697. PMC 16204. PMID 10706618. الوسيط
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تم تجاهله (مساعدة) - "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proceedings of the National Academy of Sciences of the United States of America. 97 (7): 3491–6. Mar 2000. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800. الوسيط
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تم تجاهله (مساعدة) - "Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily". Cancer Research. 61 (22): 8094–9. Nov 2001. PMID 11719434. الوسيط
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تم تجاهله (مساعدة) - "Nucleotide alteration of retinoblastoma protein-interacting zinc finger gene, RIZ, in human leukemia". The Tohoku Journal of Experimental Medicine. 196 (3): 193–201. Mar 2002. doi:10.1620/tjem.196.193. PMID 12002276. الوسيط
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تم تجاهله (مساعدة) - "Frameshift mutations of RIZ, but no point mutations in RIZ1 exons in malignant melanomas with deletions in 1p36". Oncogene. 21 (19): 3038–42. May 2002. doi:10.1038/sj.onc.1205457. PMID 12082534. الوسيط
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تم تجاهله (مساعدة) - "Altered expression of retinoblastoma protein-interacting zinc finger gene, RIZ, in human leukaemia". British Journal of Haematology. 119 (4): 940–8. Dec 2002. doi:10.1046/j.1365-2141.2002.03972.x. PMID 12472571. الوسيط
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تم تجاهله (مساعدة) - "Biallelic inactivation of the RIZ1 gene in human gastric cancer". Oncogene. 22 (44): 6954–8. Oct 2003. doi:10.1038/sj.onc.1206403. PMID 14534544. الوسيط
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تم تجاهله (مساعدة) - "Inactivation of a histone methyltransferase by mutations in human cancers". Cancer Research. 63 (22): 7619–23. Nov 2003. PMID 14633678. الوسيط
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تم تجاهله (مساعدة) - "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Aug 2004. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. الوسيط
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تم تجاهله (مساعدة) - "Detection of frameshift mutations of RIZ in gastric cancers with microsatellite instability". World Journal of Gastroenterology. 10 (18): 2719–22. Sep 2004. doi:10.3748/wjg.v10.i18.2719. PMID 15309726. الوسيط
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تم تجاهله (مساعدة) - "The Zn-finger domain of RIZ protein promotes MCF-7 cell proliferation". Cancer Letters. 215 (2): 229–37. Nov 2004. doi:10.1016/j.canlet.2004.05.014. PMID 15488642. الوسيط
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تم تجاهله (مساعدة) - "A deletion polymorphism in the RIZ gene, a female sex steroid hormone receptor coactivator, exhibits decreased response to estrogen in vitro and associates with low bone mineral density in young Swedish women". The Journal of Clinical Endocrinology and Metabolism. 89 (12): 6173–8. Dec 2004. doi:10.1210/jc.2004-0403. PMID 15579774. الوسيط
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