WASF1

WASP family member 1
المعرفات
الأسماء المستعارة	homology of dictyostelium scar 1, WASP family protein member 1, verprolin homology domain-containing protein 1, WAS protein family member 1, wiskott-Aldrich syndrome protein family member 1, WASF1, protein WAVE-1
معرفات خارجية
أورثولوج
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

WASF1‏ (WAS protein family member 1) هوَ بروتين يُشَفر بواسطة جين WASF1 في الإنسان.^[1]^[2]^[3]

الوظيفة[عدل]

الأهمية السريرية[عدل]

المراجع[عدل]

^ "Entrez Gene: WASF1 WAS protein family, member 1". مؤرشف من الأصل في 2010-12-05.
^ Machesky LM، Insall RH (مارس 1999). "Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex". Curr Biol. ج. 8 ع. 25: 1347–56. DOI:10.1016/S0960-9822(98)00015-3. PMID:9889097.
^ Miki H، Suetsugu S، Takenawa T (فبراير 1999). "WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac". EMBO J. ج. 17 ع. 23: 6932–41. DOI:10.1093/emboj/17.23.6932. PMC:1171041. PMID:9843499.

قراءة متعمقة[عدل]

Sloane JA، Vartanian TK (2007). "WAVE1 and regulation of actin nucleation in myelination". The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. ج. 13 ع. 5: 486–91. DOI:10.1177/1073858407299423. PMID:17901257.
Whitebread S، Mele M، Kamber B، de Gasparo M (1989). "Preliminary biochemical characterization of two angiotensin II receptor subtypes". Biochem. Biophys. Res. Commun. ج. 163 ع. 1: 284–91. DOI:10.1016/0006-291X(89)92133-5. PMID:2775266.
Kitamura T، Kitamura Y، Yonezawa K، وآخرون (1996). "Molecular cloning of p125Nap1, a protein that associates with an SH3 domain of Nck". Biochem. Biophys. Res. Commun. ج. 219 ع. 2: 509–14. DOI:10.1006/bbrc.1996.0264. PMID:8605018.
Nagase T، Seki N، Ishikawa K، وآخرون (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. ج. 3 ع. 5: 321–9, 341–54. DOI:10.1093/dnares/3.5.321. PMID:9039502.
She HY، Rockow S، Tang J، وآخرون (1997). "Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells". Mol. Biol. Cell. ج. 8 ع. 9: 1709–21. DOI:10.1091/mbc.8.9.1709. PMC:305731. PMID:9307968.
Witke W، Podtelejnikov AV، Di Nardo A، وآخرون (1998). "In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly". EMBO J. ج. 17 ع. 4: 967–76. DOI:10.1093/emboj/17.4.967. PMC:1170446. PMID:9463375.
Bear JE، Rawls JF، Saxe CL (1998). "SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development". J. Cell Biol. ج. 142 ع. 5: 1325–35. DOI:10.1083/jcb.142.5.1325. PMC:2149354. PMID:9732292.
Wu Y، Dowbenko D، Lasky LA (1998). "PSTPIP 2, a second tyrosine phosphorylated, cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphatase". J. Biol. Chem. ج. 273 ع. 46: 30487–96. DOI:10.1074/jbc.273.46.30487. PMID:9804817.
Suetsugu S، Miki H، Takenawa T (1999). "Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex". Biochem. Biophys. Res. Commun. ج. 260 ع. 1: 296–302. DOI:10.1006/bbrc.1999.0894. PMID:10381382.
Banin S، Gout I، Brickell P (1999). "Interaction between Wiskott-Aldrich Syndrome protein (WASP) and the Fyn protein-tyrosine kinase". Mol. Biol. Rep. ج. 26 ع. 3: 173–7. DOI:10.1023/A:1006954206151. PMID:10532312.
Higgs HN، Blanchoin L، Pollard TD (1999). "Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization". Biochemistry. ج. 38 ع. 46: 15212–22. DOI:10.1021/bi991843. PMID:10563804.
Westphal RS، Soderling SH، Alto NM، وآخرون (2000). "Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold". EMBO J. ج. 19 ع. 17: 4589–600. DOI:10.1093/emboj/19.17.4589. PMC:302050. PMID:10970852.
Prehoda KE، Scott JA، Mullins RD، Lim WA (2000). "Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex". Science. ج. 290 ع. 5492: 801–6. DOI:10.1126/science.290.5492.801. PMID:11052943.
Miki H، Yamaguchi H، Suetsugu S، Takenawa T (2001). "IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling". Nature. ج. 408 ع. 6813: 732–5. DOI:10.1038/35047107. PMID:11130076.
Marchand JB، Kaiser DA، Pollard TD، Higgs HN (2001). "Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex". Nat. Cell Biol. ج. 3 ع. 1: 76–82. DOI:10.1038/35050590. PMID:11146629.
Eden S، Rohatgi R، Podtelejnikov AV، وآخرون (2002). "Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck". Nature. ج. 418 ع. 6899: 790–3. DOI:10.1038/nature00859. PMID:12181570.
Yarar D، D'Alessio JA، Jeng RL، Welch MD (2003). "Motility determinants in WASP family proteins". Mol. Biol. Cell. ج. 13 ع. 11: 4045–59. DOI:10.1091/mbc.E02-05-0294. PMC:133613. PMID:12429845.
Soderling SH، Binns KL، Wayman GA، وآخرون (2003). "The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling". Nat. Cell Biol. ج. 4 ع. 12: 970–5. DOI:10.1038/ncb886. PMID:12447388.

هذه بذرة مقالة عن جين على كروموسوم 6 بحاجة للتوسيع. فضلًا شارك في تحريرها.

[entrez-1] "Entrez Gene: WASF1 WAS protein family, member 1". مؤرشف من الأصل في 2010-12-05.

[pmid9889097-2] Machesky LM، Insall RH (مارس 1999). "Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex". Curr Biol. ج. 8 ع. 25: 1347–56. DOI:10.1016/S0960-9822(98)00015-3. PMID:9889097.

[pmid9843499-3] Miki H، Suetsugu S، Takenawa T (فبراير 1999). "WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac". EMBO J. ج. 17 ع. 23: 6932–41. DOI:10.1093/emboj/17.23.6932. PMC:1171041. PMID:9843499.

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