WASF3

WASP family member 3
المعرفات
الأسماء المستعارة	verprolin homology domain-containing protein 3, protein WAVE-3, WASP family Verprolin-homologous protein 3, wiskott-Aldrich syndrome protein family member 3, WASF3, WAS protein family member 3
معرفات خارجية
أورثولوج
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

WASF3‏ (WAS protein family member 3) هوَ بروتين يُشَفر بواسطة جين WASF3 في الإنسان.^[1]^[2]

الوظيفة[عدل]

الأهمية السريرية[عدل]

المراجع[عدل]

^ Suetsugu S، Miki H، Takenawa T (يوليو 1999). "Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex". Biochem Biophys Res Commun. ج. 260 ع. 1: 296–302. DOI:10.1006/bbrc.1999.0894. PMID:10381382.
^ "Entrez Gene: WASF3 WAS protein family, member 3". مؤرشف من الأصل في 2010-12-05.

قراءة متعمقة[عدل]

Jones GE (2000). "Cellular signaling in macrophage migration and chemotaxis". J. Leukoc. Biol. ج. 68 ع. 5: 593–602. PMID:11073096.
Nakajima D، Okazaki N، Yamakawa H، وآخرون (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. ج. 9 ع. 3: 99–106. DOI:10.1093/dnares/9.3.99. PMID:12168954.
Schott DR، Chang JN، Deng G، وآخرون (1994). "A candidate tumor suppressor gene in human breast cancers". Cancer Res. ج. 54 ع. 6: 1393–6. PMID:8137235.
Bonaldo MF، Lennon G، Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. ج. 6 ع. 9: 791–806. DOI:10.1101/gr.6.9.791. PMID:8889548.
Bear JE، Rawls JF، Saxe CL (1998). "SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development". J. Cell Biol. ج. 142 ع. 5: 1325–35. DOI:10.1083/jcb.142.5.1325. PMC:2149354. PMID:9732292.
Nagase T، Ishikawa K، Suyama M، وآخرون (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. ج. 5 ع. 6: 355–64. DOI:10.1093/dnares/5.6.355. PMID:10048485.
Marchand JB، Kaiser DA، Pollard TD، Higgs HN (2001). "Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex". Nat. Cell Biol. ج. 3 ع. 1: 76–82. DOI:10.1038/35050590. PMID:11146629.
Millard TH، Machesky LM (2001). "The Wiskott-Aldrich syndrome protein (WASP) family". Trends Biochem. Sci. ج. 26 ع. 3: 198–9. DOI:10.1016/S0968-0004(01)01788-1. PMID:11246027.
Sossey-Alaoui K، Su G، Malaj E، وآخرون (2002). "WAVE3, an actin-polymerization gene, is truncated and inactivated as a result of a constitutional t(1;13)(q21;q12) chromosome translocation in a patient with ganglioneuroblastoma". Oncogene. ج. 21 ع. 38: 5967–74. DOI:10.1038/sj.onc.1205734. PMID:12185600.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Sossey-Alaoui K، Head K، Nowak N، Cowell JK (2003). "Genomic organization and expression profile of the human and mouse WAVE gene family". Mamm. Genome. ج. 14 ع. 5: 314–22. DOI:10.1007/s00335-002-2247-7. PMID:12856283.
Dunham A، Matthews LH، Burton J، وآخرون (2004). "The DNA sequence and analysis of human chromosome 13". Nature. ج. 428 ع. 6982: 522–8. DOI:10.1038/nature02379. PMC:2665288. PMID:15057823.
Oda A، Miki H، Wada I، وآخرون (2005). "WAVE/Scars in platelets". Blood. ج. 105 ع. 8: 3141–8. DOI:10.1182/blood-2003-04-1319. PMID:15280206.
Kashiwagi H، Shiraga M، Kato H، وآخرون (2005). "Expression and subcellular localization of WAVE isoforms in the megakaryocyte/platelet lineage". J. Thromb. Haemost. ج. 3 ع. 2: 361–8. DOI:10.1111/j.1538-7836.2004.01082.x. PMID:15670045.
Stovold CF، Millard TH، Machesky LM (2006). "Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2". BMC Cell Biol. ج. 6: 11. DOI:10.1186/1471-2121-6-11. PMC:555569. PMID:15752430.{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link)
Sossey-Alaoui K، Li X، Ranalli TA، Cowell JK (2005). "WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase". J. Biol. Chem. ج. 280 ع. 23: 21748–55. DOI:10.1074/jbc.M500503200. PMID:15826941.
Sossey-Alaoui K، Ranalli TA، Li X، وآخرون (2005). "WAVE3 promotes cell motility and invasion through the regulation of MMP-1, MMP-3, and MMP-9 expression". Exp. Cell Res. ج. 308 ع. 1: 135–45. DOI:10.1016/j.yexcr.2005.04.011. PMID:15907837.

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

[1] Suetsugu S، Miki H، Takenawa T (يوليو 1999). "Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex". Biochem Biophys Res Commun. ج. 260 ع. 1: 296–302. DOI:10.1006/bbrc.1999.0894. PMID:10381382.

[2] "Entrez Gene: WASF3 WAS protein family, member 3". مؤرشف من الأصل في 2010-12-05.

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